Isibulali-ntsholongwane sotywala esintsonkothileyo sisisombululo esisebenzayo sokubulala iintsholongwane, iintsholongwane, kunye neentsholongwane kumphezulu.Ifomula idibanisa iintlobo ezahlukeneyo zotywala, ezifana ne-isopropanol kunye ne-ethanol, kunye nezinye izithako zokwenza isibulali-ntsholongwane esinamandla esikhuselekileyo ukuba sisetyenziswe kwiindawo ezahlukeneyo.Isibulali-ntsholongwane esintsonkothileyo esinxilisayo kulula ukusisebenzisa kwaye sikhawuleza sibe ngumphunga, singashiyi ntsalela ngasemva.Ilungele ukusetyenziswa ezibhedlele, iikliniki, ezikolweni, nakwezinye iindawo ezinabantu abaninzi bezithuthi apho ukusasazeka kweentsholongwane kuxhalabisayo.