Izinhlanganisela zotshwala zibhekisela ezinhlobonhlobo zamakhemikhali ahlanganisa iqembu elilodwa noma ngaphezulu le-hydroxyl functional (-OH).Lezi zinhlanganisela zisetshenziswa ezintweni ezehlukene, njengezincibilikisi, izibulala-magciwane, i-antifreeze, nezithasiselo zikaphethiloli.I-Ethanol, i-methanol, ne-isopropanol yizinhlanganisela zotshwala ezivame kakhulu ezisetshenziswa embonini nempilo yansuku zonke.Izinhlanganisela zotshwala nazo ziyasetshenziswa ekukhiqizeni imithi, izimonyo, nezinongo zokudla.Nokho, ukuphuza ngokweqile kungaba nemiphumela emibi empilweni yomuntu, okuhlanganisa ukulimala kwesibindi, ukulutheka, nokufa.Ngakho-ke, kubalulekile ukusebenzisa izinhlanganisela zotshwala ngokuzibophezela nangokuhambisana neziqondiso zokuphepha.